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CALIFORNIA LEGISLATURE— 2025–2026 REGULAR SESSION House Resolution No. 85 Introduced by Assembly Member Nguyen February 12, 2026 Relative to Angelman Syndrome Awareness Day. LEGISLATIVE COUNSEL'S DIGEST HR 85, as introduced, Nguyen. Digest Key Bill Text WHEREAS, Angelman syndrome is a rare neurogenetic disorder that occurs in 1 in 15,000 live births and affects approximately 500,000 individuals worldwide; and WHEREAS, Angelman syndrome is caused by a loss of function of the UBE3A gene in chromosome 15 derived from the mother, and a gene that is needed to develop and control speech and movement; and WHEREAS, Individuals with Angelman syndrome begin experiencing developmental delays starting from 6 and 12 months of age, inclusive, and these developmental delays are often the first signs of Angelman syndrome; and WHEREAS, In addition to delayed development, Angelman syndrome causes problems with speech and balance, mental disability, and sometimes seizures; and WHEREAS, Angelman syndrome shares symptoms and characteristics with other disorders, including autism, cerebral palsy, and Prader-Willi syndrome; and WHEREAS, Individuals with Angelman syndrome have an overall happy and excitable demeanor, and they smile and laugh often; and WHEREAS, Angelman syndrome is rare. Most individuals with Angelman syndrome do not have a family history of the syndrome, and researchers often do not know what causes the genetic changes that result in the disease; and WHEREAS, Angelman syndrome can lead to several complications, including trouble feeding, hyperactivity, sleep troubles, scoliosis, and obesity; and WHEREAS, The treatment of Angelman syndrome focuses on managing medical, sleep, and developmental issues; and WHEREAS, There is currently no cure for Angelman syndrome, but organizations such as the Angelman Syndrome Foundation note that with further research, there may be a cure in the future; and WHEREAS, Organizations worldwide recognize February 15 as International Angelman Day to raise awareness about Angelman syndrome; now, therefore, be it Resolved by the Assembly of the State of California, That the Assembly hereby recognizes February 15, 2026, as Angelman Syndrome Awareness Day; and be it further Resolved, That the Chief Clerk of the Assembly transmit copies of this resolution to the author for appropriate distribution.